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Surgical Management of Spondyloarthropathies in the Age of Disease Altering Drugs

Teaser: 

1Mosaab Alsuwaihel, MD, 2Sean Christie, MD,

1PGY4 Dalhousie Neurosurgery Program, Dalhousie University, Halifax, NS. 2Professor, Department of Surgery (Neurosurgery), Faculty of Medicine, Vice-Chair and Director of Research , Division of Neurosurgery, Dalhousie University.

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Abstract: Inflammatory spondyloarthropathies produce synovitis of the spinal joints in rheumatoid arthritis (RA), or enthesitis in ankylosing spondylitis (AS). In RA, progressive disease leads to synovial destruction, ligamentous laxity, pannus formation and deformity. In AS progressive enthesitis results in ascending ossification, kyphotic deformity and rigidity which increase the risk of fracture. Although pain is the common presentation, spinal cord compression can produce neurological deficits. Although the need for surgery has decreased with the advent of new disease altering drugs, there remains a number of indications when surgical consultation remains important.
Key Words: Spondyloarthropathy and spondyloarthritis, Synovium and synovitis, Enthesis and enthesitis, Pannus.

Members of the College of Family Physicians of Canada may claim MAINPRO-M2 Credits for this unaccredited educational program.

www.cfpc.ca/Mainpro_M2

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Pre-test CME Quiz Post-test CME Quiz
1. Inflammatory arthritis from multiple etiologies may affect the spine with different patterns and pathophysiology.
2. Rheumatoid arthritis is a disease of synovial inflammation and in advanced disease leads to synovitis within the atlanto-dental articulation and the facet joints of the spine.
3. If left untreated atlantoaxial subluxation, cranial settling and pannus formation may lead to spinal cord and lower medullary compression.
4. Seronegative arthropathies leads to an enthesitis of the spine, usually starting in the sacroiliac spine and ascending with progressive ossification.
5. As a consequence of pathological alteration of the spine biomechanics, trauma in the setting of ankylosing spondylitis leads to different fracture patterns with a high chance of instability even after minimal trauma.
1. Early and adequate treatment of rheumatoid arthritis can prevent advanced atlanto-axial disease, deformity and neurological injury.
2. Even minimal trauma to the spine in a patient with ankylosing spondylitis has a high risk of instability and neurological injury; detailed imaging is always warranted.
3. With the advent of modern disease modifying agents for the treatment of spondyloarthropathies, the requisite for surgery has decreased but there remain important indications.
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Related Terms: Back Health, Spondyloarthropathy and spondyloarthritis, Synovium and synovitis, Enthesis and enthesitis, Pannus
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Athletes and their Hearts: What the Primary Care Physician Should Recognize

Teaser: 

Dr. Marina Abdel Malak

is a Family Medicine Resident at the University of Toronto. She graduated and completed her Bachelor of Science in Nursing and went on to study Medicine. She has a passion for medical education, patient empowerment, and increasing awareness about the relationship between mental, emotional, and physical health.

CLINICAL TOOLS

Abstract: Physicians will undoubtedly follow athletic patients in their practice, and must therefore be aware of the cardiac adaptations that occur in these patients. Athletic heart syndrome (AHS) is a term used to describe the physiologic adaptation (leading to cardiac hypertrophy and/or dilation) that the heart undergoes in response to intense physical activity. Although these are adaptive responses, physicians need to ensure that these changes are not due to pathological causes such as hypertrophic cardiomyopathy, other genetic or congenital disorders, etc. To do so, physicians must take a through history from the athlete (including family history), conduct a physical exam, and order investigations (such as ECGs, an echocardiograph, etc.) as appropriate. If a pathologic cause is not identified and AHS is noted to be the sole cause of these changes, the athlete should still be counselled on how to safely participate in physical activity.
Key Words: Athletes, cardiovascular care, sports medicine, primary care, screening.
Athletic heart syndrome (AHS) is a physiologic adaptation hypertrophy and/or dilation of the heart that allows for increased stroke volume, decreased heart rate, and increased blood flow and oxygen delivery
The hypertrophy and/or dilation that occurs in AHS can mimic serious illnesses that must be ruled out
To differentiate between AHS and pathological causes of AHS, the physician should take a history and conduct a physical exam. Echocardiography and an ECG are also important
A family history of sudden cardiac death (SCD) is a 'red flag' that must be investigated further
Inquire and investigate for symptoms such as syncope, shortness of breath, connective tissue changes, lab abnormalities, etc. It is important to keep the differential diagnosis broad to ensure a serious cardiovascular condition isn't missed
An echocardiogram should be ordered to assess cardiac function and look for structural changes in the heart
When other causes have been ruled out, AHS may be diagnosed. Although this is not inherently dangerous in itself, all athletes engaging in strenuous activity require counselling and advice around warming up, pacing activity, etc.
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Related Terms: Cardio-Cerebrovascular, athletes, cardiovascular care, sports medicine, primary care, screening
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Primary Care Approach to Degenerative Cervical Myelopathy

Teaser: 

1Ali Moghaddamjou, MD,2Jetan H. Badhiwala, MD,3Michael G. Fehlings. MD, Phd, FRCSC, FACS,

1Division of Neurosurgery, Department of Surgery, University of Toronto, Spinal Program, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada. 2Division of Neurosurgery, Department of Surgery, University of Toronto, Spinal Program, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada. 3Division of Neurosurgery, Department of Surgery, University of Toronto, Spinal Program, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.

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Abstract: Degenerative cervical myelopathy is an umbrella term describing all degenerative conditions that present with cervical myelopathy due to compression of the spinal cord. The role of primary care physicians (PCPs) in early identification is vital as delayed diagnosis can lead to irreversible neurological impairment. Patients often present with subtle neurological deficits associated with neck or upper extremity pain. Screening for upper motor neuron signs, gait disturbances, fine motor abnormalities and bowel bladder symptoms is critical. Currently, surgical decompression is the treatment of choice but with future advancements in non-operative treatments, PCPs are expected to play a larger role in treatment plans.
Key Words: degenerative cervical myelopathy, primary care, cervical spondylotic myelopathy, degenerative disc disease.

Members of the College of Family Physicians of Canada may claim MAINPRO-M2 Credits for this unaccredited educational program.

www.cfpc.ca/Mainpro_M2

You can take quizzes without subscribing; however, your results will not be stored. Subscribers will have access to their quiz results for future reference.

Pre-test CME Quiz Post-test CME Quiz
PCPs play a vital role in the management of DCM as a delayed diagnosis can lead to irreversible neurological impairment.
A heightened level of awareness with a comprehensive history and a focused physical examination are essential.
With advancements in biomarkers and emerging neuroprotective and regenerative agents, we can expect an increased role in the primary care medical management of DCM patients soon.
The approach to DCM management is multidisciplinary and generally will involve PCPs, spinal surgeon, physiotherapist, pain specialist, and neurologist.
Patients with query bilateral carpal tunnel syndrome should be assessed for DCM.
Patients with moderate to severe DCM or unequivocal progression of mild DCM require surgical treatment while there exists clinical equipoise between structured non-operative therapies and surgical decompression for mild non-progressive cases of DCM.
Clinically monitor patients with mild DCM frequently and carefully for subtle signs of neurological progression
To have access to full article that these tools were developed for, please subscribe. The cost to subscribe is $80 USD per year and you will gain full access to all the premium content on www.healthplexus.net, an educational portal, that hosts 1000s of clinical reviews, case studies, educational visual aids and more as well as within the mobile app.
Related Terms: Back Health, degenerative cervical myelopathy, primary care, cervical spondylotic myelopathy, degenerative disc disease
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