Sameer Satija, MD, Clinical Fellow, Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA.
Nanette K. Wenger, MD, Professor of Medicine (Cardiology), Emory University School of Medicine, Atlanta; Chief of Cardiology, Grady Memorial Hospital, Atlanta, GA, USA.

Chronic angina is a common problem among older adults. The burden of coronary heart disease in patients over age 75 is high. Coronary angiography, percutaneous coronary intervention with or without stenting, and coronary artery bypass graft surgery all entail higher risk in the older population. Nevertheless, patients older than 75 also may accrue a greater benefit, given their increased risk for overall cardiac mortality. We suggest a measured approach to revascularization in older adults with chronic angina, considering their severity of symptoms, the adequacy of treatment of angina, their left ventricular ejection fraction, patient preference, other comorbidities, and ischemic burden identified by noninvasive testing.
Key words: angina, revascularization, older adults, coronary disease, coronary angiography.

Carla Miller, PhD, RD, Associate Professor, Department of Human Nutrition, Ohio State University, Columbus, OH, USA.

The translation of effective treatments for obesity and diabetes management into clinical care has been slow. However, self-management education and counselling regarding diet and physical activity can improve weight, blood glucose, and lipid levels, and blood pressure control among older adults with type 2 diabetes. A collaborative approach to counselling is more effective than simply lecturing in promoting and sustaining behaviour change. The five A’s to behavioural counselling—assess, advise, agree, assist, and arrange—provide a model for care. A key component of the five A’s for counselling is the development of an action plan that specifies goals and implementation intentions for behaviour change.
Key words: type 2 diabetes mellitus, older adults, behavioural research, patient education, behavioural therapy.

Mae Sheikh-Ali, MD, Assistant Professor of Medicine, University of Florida College of Medicine, Division of Endocrinology Diabetes and Metabolism, Department of Medicine, University of Florida College of Medicine, Jacksonville, FL, USA.
Joe M. Chehade, MD, Associate Professor of Medicine, University of Florida College of Medicine, Division of Endocrinology Diabetes and Metabolism, Department of Medicine, University of Florida College of Medicine, Jacksonville, FL, USA.

Over the past decade, eight classes of drugs have been used to treat diabetes; however, insulin remains the most effective and least costly treatment for older adults. The American Diabetes Association has recommended that the approach to drug therapy of diabetes consider insulin a first-tier therapy. Nevertheless, there is a general reluctance among physicians and patients alike to accept insulin. The initiation of insulin therapy is especially challenging in older adults, who often have multiple comorbidities and physical limitations. In this article, we present a case-based approach to the initiation of insulin therapy in older adults.
Key words: diabetes, older adults, insulin therapy, glycemic goals, antihyperglycemic agents.

Ajay Sood, MD, Division of Clinical and Molecular Endocrinology, Case Western Reserve University School of Medicine; Louis Stokes Cleveland Veterans Affairs (VA) Medical Center, Cleveland, OH, USA.
David C. Aron, MD, MS, Division of Clinical and Molecular Endocrinology, Case Western Reserve University School of Medicine; VA Network 10 Geriatric Research, Education, and Clinical Centers, VA Health Services Research and Development Quality Enhancement Research Initiative Diabetes Clinical Coordinating Center; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.

Glycemic goals and the decision to intensify glycemic control among older adults with diabetes must be individualized based on comorbid conditions and the risks associated with treatment. The duration of diabetes mellitus, baseline glycosylated hemoglobin value, prior history of cardiovascular disease, and history of severe hypoglycemia are important factors to consider. This article reviews how the management of diabetes mellitus in this subgroup is changing in view of three recently reported randomized trials of intensive glycemic control.
Key words: diabetes, older adults, glycemic control, cardiovascular disease, glycemic goal.

Ali A. Rizvi, MD, Professor of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of South Carolina School of Medicine, Columbia, South Carolina, USA.

Recent therapeutic advances have seen the emergence of several oral agents for type 2 diabetes, providing an opportunity for better management of the disease. Older adults may pose a special challenge because of altered drug kinetics, the presence of other medical conditions, an increased propensity to adverse reactions, and a lack of evidence-based information for clinical decision making. Consideration should be given to treatment satisfaction, side effects, and the overall risk-benefit ratio of oral medications. It is important for providers to become familiar with the medication profiles and follow a rational initiation and titration regimen tailored to the individual patient.
Key words: diabetes, older adults, hyperglycemia, oral medications, combination therapy.

Judith Glaser, DO, Resident, Physical Medicine and Rehabilitation, New York University School of Medicine, Rusk Institute of Rehabilitation Medicine, New York, NY, USA.
Lydia Rolita, MD, Instructor, Section of Geriatrics, Department of Medicine, New York University School of Medicine, Bellevue Hospital Geriatric Clinic, New York, NY, USA.

The number of over-the-counter (OTC) medications is increasing as more prescription medications are being switched to OTC status. Many older adults rely on self-management of medications to treat common medical conditions such as the common cold, pain, diarrhea, and constipation. Although OTC medications are regulated by the U.S. Food and Drug Administration and Health Canada, many people are unaware of proper dosing, side effects, adverse drug reactions, and possible medication interactions that may not be clearly labelled. This article reviews the major side effects of common OTC medications and how to recognize these adverse effects, and provides health care professionals with information to offer to older adults and their caregivers about safe OTC medication use.
Key words: over-the-counter, self-medication, older adults, side effects, patient education.

Jason Strauss, MD, Departments of Psychiatry and Medicine, Division of Gerontology, Harvard Medical School; Beth Israel Deaconess Medical Center, Boston, MA; Hebrew Rehabilitation Center, Roslindale, MA; Cambridge Health Alliance, Cambridge, MA, USA.

Sleep disturbances are frequently seen among older adults with dementia, leading to significant distress for both patients and their caregivers. It is likely that neuronal loss in key areas of the brain contributes to sleep disturbances in this population. When evaluating older adults with dementia and insomnia, try to obtain information regarding all details of their sleep, and determine whether medical, psychiatric, or environmental factors may be contributors. In treating sleep disturbances in older adults with dementia, behavioural interventions should first be used to improve sleep hygiene. At the present time, there are not enough data to standardize recommendations for pharmacological treatment of insomnia in this population, so treatment should be guided by attempting to minimize potential side effects and interactions with other medications.
Key words: sleep, dementia, older adults, sleep hygiene, pharmacological treatment of insomnia.

Marc Ginsburg, RN, MScN, NP, Medical Student, University of Sint Eustatius School of Medicine, Sint Eustatius, Netherlands-Antilles.
Shawna Silver, MD, PEng, Resident, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON.
Hershl Berman, MD, FRCPC, Assistant Professor, Faculty of Medicine, University of Toronto; Staff Physician, Department of Medicine, University Health Network; Associated Medical Services Fellow in End-of-Life Care Education, University of Toronto; Centre for Innovation In Complex Care, University Health Network, Toronto, ON.

The use of opioid medications and converting among them in the older adult population can often be challenging. Physiological changes in older adults may affect metabolism and cognitive abilities. Due to renally cleared metabolites, some opioids, such as morphine, should be used with caution among older adults. Others, such as meperidine, should never be used at all. When prescribing or changing opioids, the choice of the correct formulation, appropriate counselling, and close follow-up are essential for optimal pain management and in order to prevent adverse outcomes.
Key words: opioids, pain management, older adults, analgesia, opioid conversion.

Aileen Burford-Mason, PhD, President, Holistic Health Research Foundation of Canada, Toronto, ON.

Accumulated research evidence suggests that vitamin D deficiency or insufficiency has profound implications for health and well-being, compromising immune responses and increasing the risk for osteoporosis, arthritis, diabetes, depression, cancer, and cardiovascular disease. Older adults, especially those who are housebound, are at increased risk for vitamin D deficiency. In addition to sun avoidance and the use of sunscreen, age, ethnicity, and obesity are risk factors for vitamin D deficiency. This article discusses the use of serum 25-hydroxyvitamin D to assess vitamin D needs and outlines current recommendations on appropriate interventions to improve vitamin D status in older adults.
Key words: vitamin D, older adults, supplements, UVB exposure, immunity.

Jason Andrade, MD, Division of Cardiology, University of British Columbia, Department of Medicine, Vancouver, BC.
Aneez Mohamed, MD, Division of Cardiology, University of British Columbia, Department of Medicine, Vancouver, BC.
Chris Rauscher, MD, Division of Geriatric Medicine, University of British Columbia, Department of Medicine, Vancouver, BC.

Infective endocarditis (IE) is a rare but potentially devastating clinical entity with a well-delineated pathogenesis. While previously thought to be a disorder of younger individuals, older adults now represent one of the highest risk groups for the acquisition of and adverse outcomes related to IE. Prior to focusing on the updated recommendations for IE prophylaxis and the rationale behind them, we briefly review the clinical aspects of IE in the general population, as well as special considerations for older adults.
Key words: endocarditis, prophylaxis, older adults, cardiovascular disease, antibiotics.