Scientist at the University of Ottawa have constructed human corneal equivalents from synthetic materials, polymers and immortal human corneal cell lines. The artificial corneas were able to mimic human corneas in key physiological and physical functions. Functional equivalents to human corneas that can be produced in vitro have immediate applications in testing for drug efficacy and toxicity. Although more research is needed before lab-grown corneas can be transplanted, these cells form the basis for future development of implantable tissues.
- Griffith et al. Science. 1999;286:2169.
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